Restlessness and agitation. Symptoms and signs involving emotional state
Conditions
Interventions
Intervention 1: intra nasal midazolam 0.2 mg/kg ,45-60 minutes before induction. Intervention 2: Intranasal ketamine 8mg/kg ,45-60 minutes before induction. Intervention 3: Intranasal dexmedetomidine
Treatment - Drugs
intra nasal midazolam 0.2 mg/kg ,45-60 minutes before induction
Intranasal ketamine 8mg/kg ,45-60 minutes before induction
Intranasal dexmedetomidine 1.5 mic /kg ,45-60 minutes before induction
Sponsors
Shiraz University of Medical Sciences. Research chancellor
Eligibility
Sex/Gender
All
Age
2 Years to 7 Years
Inclusion criteria
Inclusion criteria: inclusion criteria: children aged between 2-7 year; ASA classification I-II; unilateral inguinal herniorraphy Exclusion criteria: Hx. of hypersensitivity to drugs of the study(Midazolam; Ketamine and Dexmedetomidine); liver failure; renal failure; upper respiratory tract infection; cardiac arrythmia; congenital heart disease; neurologic disease
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anxiety. Timepoint: Every 10 min after seperation of parents. Method of measurement: Observation( Four point scale).;Pain. Timepoint: Every 15min in PACU. Method of measurement: Observation( Modified objective pain scale).;Nausea &vomiting. Timepoint: Recovery time. Method of measurement: observation.;Sedation. Timepoint: Every 10 minutes. Method of measurement: Obsevation( Modified observer's assessment alertness sedation). | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation scale in PACU. Timepoint: Every 15 min. Method of measurement: Observation( Modified observer's assessment alertness sedation). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Keihani
Shiraz University of Medical Sciences
Outcome results
None listed