The effect of exercise and grape seed extract supplementation

The effects of aerobic exercise and short-term grape seed extract supplementation on some oxidative stress indiced in men

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013081614371N1

Enrollment

Registered

2015-02-12

Start date

2012-01-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oxidative stress. Drug or medicament, unspecified

Interventions

Intervention 1: Grape seed extract, 200 mg/day, for 14 days, after the supplementation period (14 days), all subjects participate in an aerobic exercise at 75% vo2max for 30 minutes. Intervention 2: I

Placebo

Grape seed extract, 200 mg/day, for 14 days, after the supplementation period (14 days), all subjects participate in an aerobic exercise at 75% vo2max for 30 minutes

Inert, 200 mg/day, for 14 days, after the supplementation period (14 days), all subjects participate in an aerobic exercise at 75% vo2max for 30 minutes.

Eligibility

Sex/Gender

Male

Age

18 Years to 22 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Healthy male? Non-athlete? Non-Smoker?Informed consent? without any inflammatory or oxidative supplement ingestion during 6 months prior to the study, Exclusion criteria: chronic diseases? injuries.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Total antioxidant. Timepoint: 14 day after the initiation of the intervention. Method of measurement: ABTs method.;Serum Malondialdehyde. Timepoint: 14 day after the initiation of the intervention. Method of measurement: by thiobarbituric acid reactive substance (TBARS) and spectrophotometer.;Cratine kinase. Timepoint: 14 day after the initiation of the intervention. Method of measurement: by automatic analyzer and PARS azmon kit.;Blood Lactate. Timepoint: 14 day after the initiation of the intervention. Method of measurement: by automatic analyzer and GIESSE kit.;LDH. Timepoint: 14 day after the initiation of the intervention. Method of measurement: by automatic analyzer and PARS azmon kit.	—

Measure

Time frame

Total antioxidant. Timepoint: 14 day after the initiation of the intervention. Method of measurement: ABTs method.;Serum Malondialdehyde. Timepoint: 14 day after the initiation of the intervention. Method of measurement: by thiobarbituric acid reactive substance (TBARS) and spectrophotometer.;Cratine kinase. Timepoint: 14 day after the initiation of the intervention. Method of measurement: by automatic analyzer and PARS azmon kit.;Blood Lactate. Timepoint: 14 day after the initiation of the intervention. Method of measurement: by automatic analyzer and GIESSE kit.;LDH. Timepoint: 14 day after the initiation of the intervention. Method of measurement: by automatic analyzer and PARS azmon kit.

—

Secondary

Measure	Time frame
Lipid profile. Timepoint: 14 day after. Method of measurement: by automatic analyzer and PARS azmon kit.;Serum hs-CRP. Timepoint: 14 day after. Method of measurement: by automatic analyzer.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Vahid Sari-Sarraf

University of Tabriz

vsarisarraf@yahoo.comsarraf@tabrizu.ac.ir+98 41 3339 3254

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026