Bimaxillary orthognathic surgery. 00
Conditions
Interventions
Intervention 1: Patients in the first group will be received "Lidocaine" an initial dose of 1 mg / kg body weight intravenously during 5 minutes and then continuously Lidocaine 2 mg / kg / hr via pump
Treatment - Drugs
Patients in the first group will be received "Lidocaine" an initial dose of 1 mg / kg body weight intravenously during 5 minutes and then continuously Lidocaine 2 mg / kg / hr via pump infusion until
Sponsors
Vice-Chancellery of Research and Technology, Shiraz University Of Medical Sciences
Eligibility
Sex/Gender
All
Age
16 Years to 40 Years
Inclusion criteria
Inclusion criteria: Patients with no history of systemic disease and without taking any analgesic medications criteria that were willing to cooperate in this study were enrolled; and Exclusion criteria included known allergy to the study drugs; Serious adverse drug reaction to amide local anaesthetics; hepatic and renal dysfunction ; patients with heart block including second or third degree (without pacemaker) ; Severe sinoatrial block (without pacemaker) ; Use of opioid or analgesics 3 days before the study; Acute Porphyria; Accelerated idioventricular rhythm ; Bradycardia ; and Patients who did not sign the informed consent.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate and blood pressure monitoring. Timepoint: During operation and end of surgery. Method of measurement: Heart rate and blood pressure measuring device.;The severity of postoperative pain. Timepoint: In the recovery room. Method of measurement: Visual analog scale.;The amount of intraoperative bleeding. Timepoint: During surgery and in the recovery room. Method of measurement: Cc in volume suction and Surgical gauze counting. | — |
Secondary
| Measure | Time frame |
|---|---|
| Use of intraoperative blood products. Timepoint: end of operation. Method of measurement: Volume used.;Side effects of lidocaine. Timepoint: In the recovery room and the End of operation. Method of measurement: Questionnaire.;Dosage of of narcotic drugs or analgesics in ward surgery. Timepoint: In the recovery room and the End of operation. Method of measurement: Visual analog scale.;Urine volume. Timepoint: During surgery and in the recovery room. Method of measurement: Cc per patient body weight per hour.;Postoperative shivering. Timepoint: In the recovery room. Method of measurement: Observation of the patient.;Nausea and vomiting after surgery. Timepoint: In the recovery room and the End of operation. Method of measurement: Observation of the patient.;Agitation after anesthesia. Timepoint: In the recovery room and the End of operation. Method of measurement: Observation of the patient.;Dosage of of narcotic drugs or analgesics in ward surgery. Timepoint: In the ward surgery after 12 hr. Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactArash Karami
Shiraz Chamran Hospital
Outcome results
None listed