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Effect of morphine suppositories on pain control after CABG (Coronary artery bypass grafting )

Comparison of morphine sulfate and Diclofenac sodium rectal suppository effect on patients' pain control after coronary artery bypass graft surgery(CABG) in surgery candid

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013081414359N1
Enrollment
120
Registered
2013-11-17
Start date
2013-11-02
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart disease. Presence of aortocoronary bypass graft

Interventions

Intervention 1: Intervention 1) Morphine sulfate 10 mg rectal suppository (Statex ,Pharmascience co. montreal Canada), can repeat every 4 hours if needed. Intervention 2: Intervention 1) Diclofenac S
Treatment - Drugs
Intervention 1) Morphine sulfate 10 mg rectal suppository (Statex ,Pharmascience co. montreal Canada), can repeat every 4 hours if needed.
Intervention 1) Diclofenac Sodium 50 mg rectal suppository (Aburaihan pharmaceutical Co. Iran), can repeat every 4 hours if needed.

Sponsors

Vice chancellor for research of Guilan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: All patients that underwent elective CABG (Coronary artery bypass grafting ) that are not addicts and are ASA class 1 and 2 and are not allergic to the type of medications used and do not have history of COPD (Chronic obstructive-pulmonary disease) or asthma are studied. Exclusion criteria: All ICU patients that needed to undergo balloon pump or Inotropic therapy and those who received pain medications prior to extubation, those who were not alert and oriented enough and those that were uncooperative to determine VAS.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: every 4 hours after Intervention in 24 hours. Method of measurement: measure Vas.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactValli Imantalab

Guilan University of Medical Sciences

vimantalab@gums.ac.ir; vbuh.research@gmail.com+98 13 1666 2360

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026