Skip to content

Investigating growth factors and complications after implant treatment

A comparative study of the effect of leukocyte and fibrin-rich plasma (L-PRFin soft tissue thickness, tissue healing rate, pain and discomfort after peri-implant treatment in people needing dental implants (split- mouth randomized controlled trial)

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130813014350N5
Enrollment
10
Registered
2022-10-16
Start date
2022-09-23
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Soft tissue thickness, tissue healing rate, pain and discomfort after treatment around dental implants.

Interventions

This study will be an interventional split-moth study that examines the effect of using L-PRF on the success of dental implants in 1 target group and 1 control group. At the beginning of the plan, the

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 20-60 Partial edentulous patient The plaque index before surgery is less than 25%

Exclusion criteria

Exclusion criteria: smokers Pregnant and lactating women History of radiation therapy and chemotherapy Patients with active symptoms of infection such as pain, swelling, pus and abscess Untreated advanced periodontitis Blood disease and diabetes Hyperthyroidism High blood pressure

Design outcomes

Primary

MeasureTime frame
The thickness of the soft tissue around the implant. Timepoint: Baseline and 6 weeks later. Method of measurement: Measurement by periodontal probe in mm.

Secondary

MeasureTime frame
Postoperative pain assessment. Timepoint: during 7 days after surgery (days1,2,3,7). Method of measurement: Visual analog scale(VAS) index.;Soft tissue healing rate. Timepoint: Day 7 and day 14 after surgery. Method of measurement: (Landry Index) which includes tissue color, BOP, epithelialization of wound margin, presence of tissue granulation and presence of pus.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBardia Vadiati Saberi

Rasht University of Medical Sciences

bardia@gums.ac.ir+98 13 1326 3622

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026