Wheath anaphylaxia. Anaphylactic shock due to adverse food reaction
Conditions
Interventions
OFCs (oral food challenges) is performed to determine the initial dose of OIT.
In build up phase, patients take cake. if they can take it without severe reactions, they were asked to take bread A,
Treatment - Other
OFCs (oral food challenges) is performed to determine the initial dose of OIT.
In build up phase, patients take cake. if they can take it without severe reactions, they were asked to take bread A,
Sponsors
Pediatric Infections Research Center of Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
2 Years to 18 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria 1. Wheat allergic children aged over 2 years with history of severe symptoms and positive SPT 2. Elevated serum wheat specific IgE 3. Immediate reaction in open oral wheat challenge test Exclusion Criteria: • Uncontrolled asthma • Other chronic lung or renal disease • Cardiovascular disease or other significant systemic disease • Patients having poor compliance
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Level of total IgE in plasma. Timepoint: Start of oral immunothrapy,at the end of oral immunothrapy,after maintenace phase. Method of measurement: Measure of plasma level.;Level of specific IgE for wheat in plasma. Timepoint: Start of oral immunothrapy,at the end of oral immunothrapy,after maintenance phase. Method of measurement: Measure of plasma level.;Size of wheal and flare of wheat skin test. Timepoint: Start of oral immunotherapy,After maintenance phase. Method of measurement: Measure of size according millimeter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMitra sahragard
Shahid Beheshti University of Medical Sciences
Outcome results
None listed