Severe depression. Severe depressive episode without psychotic symptoms and Severe depressive episode with psychotic symptoms
Conditions
Interventions
Intervention 1: Intervention: Patients will be received etomidate 0.3 mg / Kg and succinylcholine 0.34-0.4 mg / Kg for induction of anesthesia for ECT. Intervention 2: Control: Patients will be receiv
Treatment - Drugs
Intervention: Patients will be received etomidate 0.3 mg / Kg and succinylcholine 0.34-0.4 mg / Kg for induction of anesthesia for ECT.
Control: Patients will be received 0.5-1 mg / Kg of propofol and succinylcholine 0.34-0.4 mg / Kg for anesthesia induction for ECT.
Sponsors
Kashan University of Medical Sciences, Deputy of Research
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: All patients who are candidates of electroconvulsive therapy and have following criteria: severe depression, acute mania, catatonia, cases who need immediate treatment and patients who do not respond to medications. Exclusion criteria: Ischemic heart disease, Hypertension, dysrhythmia, brain lesions.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate Pressure Product(systolic blood pressure multiplied pulse rate). Timepoint: Before and 1 min after induction, 1, 3 and 5 min after ECT. Method of measurement: Blood pressure will be measured by sphygmomanometer in mmHg and pulse rate through pulseoximeter.;Blood oxygen saturation,(SPO2). Timepoint: Before and 1 min after induction, 1, 3 and 5 min after ECT. Method of measurement: Through pulseoximeter as real numbers. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehrdad Mahdian
Kashan University of Medical Sciences
Outcome results
None listed