The Effect of Leukocyte-Platelet Rich Fibrin Injection on Scar

Evaluation of the Effect of Leukocyte-Platelet Rich Fibrin Injection on Scar Healing Following Upper Eyelid Blepharoplasty Incisions

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130812014333N275

Enrollment

Registered

2026-03-10

Start date

2026-04-04

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Scar. Hypertrophic scar

Interventions

Intervention 1: In the intervention group, 1.8 ml of activated leukocyte-platelet-rich fibrin (L-PRF) will be injected into each eyelid using an insulin syringe (BD Ultra-Fine 31 G × 0.8 mm). Interven

Eligibility

Sex/Gender

Female

Age

40 Years to No maximum

Inclusion criteria

Inclusion criteria: Over 40 years old People with cosmetic problems of the upper eyelid (such as drooping eyelids or deep wrinkles) Having general health

Exclusion criteria

Exclusion criteria: History of complex systemic diseases (such as uncontrolled diabetes, cardiovascular disease, or coagulation disorders) History of active infections in the surgical area History of new eye problems History of platelet allergy

Design outcomes

Primary

Measure	Time frame
Wound severity. Timepoint: One, two and three months after surgery. Method of measurement: Base on the Patient and Observer Scar Assessment Scale (POSAS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Asghar Nazer

Islamic Azad University, Khorasgan branch

nazer20@gmail.com+98 31 3535 4003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026