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Determining the effect of intravenous dexmedetomidine on changes in vital signs

Determining the effect of intravenous dexmedetomidine on changes in vital signs during nasal intubation in dental candidates under general anesthesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130812014333N260
Enrollment
50
Registered
2025-08-01
Start date
2025-08-11
Completion date
Unknown
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who are candidates for endotracheal intubation.

Interventions

Intervention 1: The intervention group will receive dexmedetomidine 5 mg/kg intravenously over 10 minutes in addition to the anesthetic. Intervention 2: The control group will receive normal saline 5

Sponsors

Islamic Azad University, Khorasgan branch
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Informed consent Age between 18 and 35 years old Be physically in ASA group one and two.

Exclusion criteria

Exclusion criteria: Pregnant women History of sinus disorders History of use of heart and blood pressure medications (calcium blockers, beta blockers, etc.) History of contraindications to the use of dexmedetomidine (such as atrial fibrillation, ventricular premature beats, ventricular tachycardia, bradycardia, S-T segment changes, T wave changes, liver disorders, etc.).

Design outcomes

Primary

MeasureTime frame
Heart rate. Timepoint: Before the intervention, before endotracheal intubation and 5 minutes after endotracheal intubation. Method of measurement: Using a pulse oximetry device.;Blood pressure. Timepoint: Before the intervention, before endotracheal intubation and 5 minutes after endotracheal intubation. Method of measurement: Using a pulse oximetry device.;Blood oxygen. Timepoint: Before the intervention, before endotracheal intubation and 5 minutes after endotracheal intubation. Method of measurement: Using a pulse oximetry device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNiloofar Kaviani

Islamic Azad University, Khorasgan branch

niloo1612@gmail.com+98 31 3535 4003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026