Skip to content

Studying the effect of Orthokine injection on nasal polyps

Investigating the effect of Orthokine injection after endoscopic nasal surgery on the improvement of symptoms

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130812014333N249
Enrollment
88
Registered
2025-05-25
Start date
2025-06-05
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nasal polyp. Other polyp of sinus

Interventions

Intervention 1: The intervention group will receive approximately 5 cc (2.5 cc in each nasal cavity) of Orthokine after surgery. Intervention 2: The control group will receive approximately 5 cc (2.5

Sponsors

Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Informed consent Patients between 18 and 60 years of age who have been receiving drug treatment for at least 3 months Patients diagnosed with polyposis without a history of other diseases, including tumors of the sinonasal region, etc.

Exclusion criteria

Exclusion criteria: History of underlying diseases such as immune system deficiencies

Design outcomes

Primary

MeasureTime frame
Change in endoscopic symptoms. Timepoint: Immediately, two and four weeks after injection. Method of measurement: Using the Lund-Kennedy scale.;Change in clinical symptoms. Timepoint: Immediately, two and four weeks after injection. Method of measurement: Using the SNOT-22 questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Sadatnasseri

Kermanshah University of Medical Sciences

nasserif@yahoo.com+98 83 3728 3602

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026