Idiopathic Thrombocytopenic Purpura. Immune thrombocytopenic purpura
Conditions
Interventions
Intervention 1: In the intervention group, patients will receive Nplate subcutaneously and weekly at a dose of 10 µg/kg for 3 months. If the patients platelet count is greater than 30×10^3, a dose of
Sponsors
Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: People with a diagnosis of immune thrombocytopenia that has been present for at least 6 months since the onset of the disease Age less than 18 years Serum platelet count at baseline should be greater than 30 x 103 platelets/liter Serum bilirubin level should be less than 1.5
Exclusion criteria
Exclusion criteria: Patients with secondary immune thrombocytopenia History of lupus Antiphospholipid antibody syndrome Severe life-threatening bleeding Heart, lung, liver, or kidney problems History of cancer Osteoporosis Diabetes mellitus History of taking antiplatelet drugs or nonsteroidal anti-inflammatory drugs one month before the start of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding frequency. Timepoint: Beginning of the study and end of the study. Method of measurement: Doctor's observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mohammad Reza Golpayegani
Kermanshah University of Medical Sciences
Outcome results
None listed