A comparative study of pain-relieved effect of mucosal prilocaine patches and usage of acetaminophen on elastomeric separator in orthodontic patients

A comparative study of pain-relieved effect of mucosal prilocaine patches and usage of acetaminophen on elastomeric separator in orthodontic patients: a randomized clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130812014333N214

Enrollment

Registered

2024-03-08

Start date

2024-03-18

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthodontic Pain. Encounter for other specified aftercare

Interventions

Intervention 1: In the first intervention group, mucosa pieces will be randomly placed in the buccal region of the first molars of the lower jaw on both sides, and prilocaine mucosa adhesive will be u

Eligibility

Sex/Gender

All

Age

14 Years to 25 Years

Inclusion criteria

Inclusion criteria: Age between 14 and 25 years The presence of first molar, second molar and second premolar teeth of the lower jaw with strong interproximal contacts The presence of moderate crowding in the arch of the lower jaw (high irregularity index of 2)

Exclusion criteria

Exclusion criteria: pregnancy History of liver or kidney disease History of allergy to local anesthetics History of methaemoglobinemia Chronic use of NSAIDs, sedatives, or other pain relievers

Design outcomes

Primary

Measure	Time frame
Intensity of pain. Timepoint: 2, 6, 12, and 24 hours after the intervention, bedtime, 2, 3, and 7 days after the intervention. Method of measurement: Based on Visual Analogue Scale (VAS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahya Tajjik

Kermanshah University of Medical Sciences

mahyatajjik99@gmail.com+98 83 3729 6591

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026