Comparison of the effects of clonidine and tranexamic acid on the rate of bleeding during nose surgery

Comparative study of the effects of clonidine and tranexamic acid on the rate of bleeding during rhinoplasty surgery. Clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130812014333N211

Enrollment

Registered

2023-11-25

Start date

2023-12-06

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rhinoplasty. Acquired deformity of nose

Interventions

Intervention 1: The first intervention group will receive 700 micrograms of tranexamic acid per kilogram of body weight orally two hours before surgery. Intervention 2: The second intervention group w

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Informed consent Age between 18-60 years

Exclusion criteria

Exclusion criteria: Addiction to narcotics and benzodiazepines History of seizures Suffering from liver and kidney failure, diabetes, lung and heart diseases, coagulation disorders History of allergy to clonidine and tranexamic acid drugs pregnancy

Design outcomes

Primary

Measure	Time frame
Bleeding rate. Timepoint: The beginning of the study and the end of the study. Method of measurement: Based on the amount of blood collected in the suction.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam safdari

Kermanshah University of Medical Sciences

sainasfd@gmail.com+98 83 3427 6306

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026