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Efficacy of 10% honey and 5% frankincense gel in the treatment of mucositis caused by radiotherapy in cancer patients

Investigating the effect of 10% honey and 5% frankincense gel in the treatment of mucositis caused by radiotherapy in cancer patients: a parallel, randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130812014333N197
Enrollment
60
Registered
2023-02-24
Start date
2022-12-31
Completion date
Unknown
Last updated
2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer. Disseminated malignant neoplasm, unspecified

Interventions

Intervention 1: The intervention group will use topical gel containing frankincense (10 percent) and honey twice daily for a week to ten days (the gel will be manufactured by Ariogen Sina Daru pharmac

Sponsors

Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Informed consent Radiotherapy candidate patients in such a way that at least one third of the oral mucosa is included No history of head and neck radiotherapy

Exclusion criteria

Exclusion criteria: A history of frankincense allergy receiving concurrent chemotherapy regimen (other than cisplatin or cetuximab) Patients with liver problems Diabetes and history of hypoglycemia Patients with recurrent infections The presence of similar wounds in the genital area Joint swelling and pain, eye problems such as pain, blurriness and redness Using other drugs to treat the pest

Design outcomes

Primary

MeasureTime frame
Pain intensity. Timepoint: Zero, first, sixth and tenth days. Method of measurement: Using a visual pain scale.;Sense of taste. Timepoint: The zero and seventh days of study. Method of measurement: Using Patient Reported Outcome Measures (PROMS).;Ability to swallow solid and liquid substances. Timepoint: The zero and seventh days of study. Method of measurement: Using Patient Reported Outcome Measures (PROMS).;Speech disorder. Timepoint: The zero and seventh days of study. Method of measurement: Using Patient Reported Outcome Measures (PROMS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Seyed Shahram Miraghaei

Kermanshah University of Medical Sciences

shahram.miraghaee@yahoo.com+98 83 3426 6780

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026