Comparative study of the consequences of expected treatment of premature membrane rupture in women

Comparative study of the consequences of expected treatment of premature membrane rupture in women with gestational age less than 34 weeks and gestational age of 34-36 weeks

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130812014333N179

Enrollment

Registered

2022-01-27

Start date

2022-01-15

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Premature rupture of membranes. Premature rupture of membranes, unspecified as to length of time between rupture and onset of labor, unspecified weeks of gestation

Interventions

Intervention 1: In waiting for treatment group up to 34 weeks they will receive 2 g of injectable ampicillin every 6 hours for the first 48 hours with oral erythromycin 400 mg every 6 hours. 5 days la

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women with the final diagnosis of Preterm premature rupture of the membranes (PPROM) Gestational age of 34 weeks, that up to 24 hours after rupture of the membranes having labor pains Being 34 to 36 weeks old for the waiting treatment group

Exclusion criteria

Exclusion criteria: Women with monocurion multiple pregnancies; Uncertain cardiogram Meconium contaminated amniotic fluid Fetal major anomaly HELLP syndrome or preeclampsia Symptoms of intrauterine infection

Design outcomes

Primary

Measure	Time frame
Apgar. Timepoint: The first and fifth minutes after birth. Method of measurement: Apgar test.;Duration of hospitalization of the infant in the intensive care unit (NICU). Timepoint: After discharge. Method of measurement: Based on the record.;Respiratory distress syndrome. Timepoint: After birth. Method of measurement: Clinical examination.;Sepsis. Timepoint: After birth. Method of measurement: Clinical examination.;Uterine bleeding. Timepoint: after delivery. Method of measurement: Ask the patient and the doctor observation.	—

Measure

Time frame

Apgar. Timepoint: The first and fifth minutes after birth. Method of measurement: Apgar test.;Duration of hospitalization of the infant in the intensive care unit (NICU). Timepoint: After discharge. Method of measurement: Based on the record.;Respiratory distress syndrome. Timepoint: After birth. Method of measurement: Clinical examination.;Sepsis. Timepoint: After birth. Method of measurement: Clinical examination.;Uterine bleeding. Timepoint: after delivery. Method of measurement: Ask the patient and the doctor observation.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzadeh Falahatkar

Kermanshah University of Medical Sciences

azadeh.1111@yahoo.com+98 83 3427 6306

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026