kidney transplantation. Complications of kidney transplant
Conditions
Interventions
Intervention 1: The intervention group for 12 weeks will receive empagliflozin at a dose of 10 mg daily with routine treatment (500 mg metformin two or three times daily). Intervention 2: The control
Sponsors
Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Urinary protein excretion less than (<) 500 mg to 3500 mg / g in a 24-hour urine set Kidney transplant equal to or greater than 1 year ago Stable state of renal function for at least the last three months Sustained immunosuppressive therapy for at least the last 3 months
Exclusion criteria
Exclusion criteria: Creatinine above 2 Patients who are pregnant or are breastfeeding Patients with a history of type 1 diabetes History of more than one kidney transplant; History of severe allergies or contraindications to empagliflozin History of recurrent urinary tract infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum creatinine. Timepoint: The beginning of the study, the end of the 4th week, the end of the 8th week and the end of the 12th week. Method of measurement: Blood test.;Urine protein content. Timepoint: The beginning of the study, the end of the 4th week, the end of the 8th week and the end of the 12th week. Method of measurement: urine test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Mohammad Mostafavi
Kermanshah University of Medical Sciences
Outcome results
None listed