Comparative study of hemodynamic and renal effects of Pethidine and Marcaine during and after surgery in patients undergoing ureteral stone surgery

Comparative study of hemodynamic and renal effects of Pethidine and Marcaine during and after the operation in patients undergoing TUL surgery: double-blind randomized controlled clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130812014333N165

Enrollment

Registered

2021-04-05

Start date

2021-04-18

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urological services with urine virtual stone. Calculus of lower urinary tract

Interventions

Intervention 1: The first intervention group will receive 15-15.5 mg of Markain 0.5% in the intervertebral space L3-L4 for spinal anesthesia by injection. Intervention 2: The second intervention grou

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are candidates for TUL surgery by their doctor Patients who are in ASA class 1 and 2

Exclusion criteria

Exclusion criteria: Patients with chronic diseases including heart disease and hypertension and advanced lung and neurological diseases Patients taking opium Patients who are contraindications to the spinal procedure

Design outcomes

Primary

Measure	Time frame
Blood pressure changes. Timepoint: Every 5 minutes until the end of the first 30 minutes, then every 15 minutes until the end of surgery and in the recovery room every 15 minutes until the recovery criteria are met. Method of measurement: Using a pressure gauge.;Heart rate changes. Timepoint: Every 5 minutes until the end of the first 30 minutes, then every 15 minutes until the end of surgery and in the recovery room every 15 minutes until the recovery criteria are met. Method of measurement: Using a pulse oximeter.;Urinary retention. Timepoint: Before and after anesthesia. Method of measurement: Based on questions from the patient and based on observation and clinical examination.	—

Measure

Time frame

Blood pressure changes. Timepoint: Every 5 minutes until the end of the first 30 minutes, then every 15 minutes until the end of surgery and in the recovery room every 15 minutes until the recovery criteria are met. Method of measurement: Using a pressure gauge.;Heart rate changes. Timepoint: Every 5 minutes until the end of the first 30 minutes, then every 15 minutes until the end of surgery and in the recovery room every 15 minutes until the recovery criteria are met. Method of measurement: Using a pulse oximeter.;Urinary retention. Timepoint: Before and after anesthesia. Method of measurement: Based on questions from the patient and based on observation and clinical examination.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactBahar Khodayar

Kermanshah University of Medical Sciences

Baharkhodayar@yahoo.com+98 83 3427 6306

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026