Effect of Granisetron on blood pressure drops in cesarean delivery

Study of the effect of Granisetron in the prevention of blood pressure drops after spinal anesthesia for cesarean delivery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130812014333N122

Enrollment

106

Registered

2019-05-25

Start date

2019-06-10

Completion date

Unknown

Last updated

2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Maternal hypotension. Maternal hypotension syndrome

Interventions

Intervention 1: In intervention group, patients will receive 2 mg of Granisetron 5 minutes before the spinal anesthesia via angiocontose. Then, spinal anesthesia with 15 mg of Bupivacaine will be done

Eligibility

Sex/Gender

Female

Age

15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Pregnant women aged 15-45 ASA Class 1 who are candidate for elective cesarean delivery under spinal anesthesia

Exclusion criteria

Exclusion criteria: Neurological disorders Spinal abnormalities Liver disease BMI>30

Design outcomes

Primary

Measure	Time frame
Blood pressure drop. Timepoint: Every 3 minutes to 30 minutes, and then every 10 minutes until the end of the surgery. Method of measurement: Using Holter Monitoring.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyedeh Nastaran Tavakoli Lahijani

Kermanshah University of Medical Sciences

nassitl@gmail.com+98 83 3427 6306

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026