Comparison of intravenous injection of methadone and sufentanil on hemorrhage in patients with opioid addiction under cardiac surgery

Comparative study of intravenous injection of methadone and sufentanil on hemorrhage in patients with opioid addiction under cardiopulmonary bypass surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130812014333N103

Enrollment

159

Registered

2018-10-06

Start date

2018-09-16

Completion date

Unknown

Last updated

2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease. Atherosclerotic heart disease

Interventions

Intervention 1: The first intervention group will receive 0.5 mg/kg of methadone at a dose of 0.5-2 mg, during and after surgery in ICU. Intervention 2: . The second intervention group will receive

Sponsors

Kermanshah University of Medical Sciences

Lead Sponsor

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with opioid addiction Patients undergoing bypass surgery

Exclusion criteria

Exclusion criteria: Having any history of coagulation disorder Systolic blood pressure above 160 and less than 100 Renal failure patients

Design outcomes

Primary

Measure	Time frame
The rate of bleeding. Timepoint: During the operation and in the I.C.U. Method of measurement: Based on observation doctor.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Rangani

Kermanshah University of Medical Sciences

shimarangani@YAHOO.COM+98 83 3836 0041

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026