Pediatric intractable epilepsy. Epilepsy, unspecified, intractable, without status epilepticus
Conditions
Interventions
Intervention 1: Intervention group 1: Patients were given 4 mg/kg curcumin solution daily for four weeks (Sinacurcumin®, each drop of solution contains 4 mg nanocurcumin). After a two-week washout per
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
3 Months to 16 Years
Inclusion criteria
Inclusion criteria: Have at least 4 epileptic seizures in the last 4 weeks. Has been using anticonvulsant drugs for at least the last 1 month. The child's parents have informed consent. Not having a history of exacerbating seizures. Not having a cardiovascular, liver, or kidney disorder.
Exclusion criteria
Exclusion criteria: Diagnosing a curable cause for the epilepsy. Epilepsy is secondary to a progressive or neurodegenerative brain disorder. Having a history of status epilepsy within the past 3 months. Having multiple and uncountable seizures. Lack of cooperation in taking the medicines properly.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of seizure attacks. Timepoint: baseline (before starting intervention), 4, 6,10 weeks after intervention. Method of measurement: based on clinical report of attacks. | — |
Secondary
| Measure | Time frame |
|---|---|
| . Timepoint: . Method of measurement: . | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamid Reza Rahimi
Mashhad University of Medical Sciences
Outcome results
None listed