Metabolic syndrome. Metabolic syndrome
Conditions
Interventions
Intervention 1: Patients in the intervention group receive 2 oral pills/day containing 15 mg of crocin for 8 consecutive weeks.
Crocin is a carotenoid, which is isolated and purified from the extract
Treatment - Drugs
Placebo
Patients in the intervention group receive 2 oral pills/day containing 15 mg of crocin for 8 consecutive weeks.
Crocin is a carotenoid, which is isolated and purified from the extract of saffron.
Patients in the control group receive 2 oral placebo pills/day for consecutive 8 weeks. placebo has no crocin and look like the crocin tablets.
Sponsors
Research Council of Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: the desire to participate in the study; having no previous history of angiography; having no order of emergency angiography; having 20 number anxiety; age over 18 years old;; health in the legs and hands; patients not taking the narcotic drug alcohol, ; having no previous history of mental disorder; not using anticoagulation medications; No diabetes; Do not have the risk of deep vein thrombosis. Exclusion criteria: injury or infection at the site of reflex zone therapy; anxiolytic or hypnotic drugs in the 8 hours before reflex zone therapy; condition of hemodynamic is unstable; transfer of patient to intensive care unit and cardiopulmonary resuscitation of the patient
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lipid profiles. Timepoint: Before the intervention, and 8 weeks after the intervention. Method of measurement: Laboratory analysis of the blood samples taken before the intervention and 8 weeks after the commencement of the intervention.;Inflammatory cytokines. Timepoint: Before the intervention, and 8 weeks after the intervention. Method of measurement: Laboratory analysis of the blood samples taken before the intervention and 8 weeks after the commencement of the intervention.;Fast blood sugar (FBS). Timepoint: Before the intervention, and 8 weeks after the intervention. Method of measurement: Laboratory analysis of the blood samples taken before the intervention and 8 weeks after the commencement of the intervention.;Pro-oxidants- antioxidants balance (PAB). Timepoint: Before the intervention, and 8 weeks after the intervention. Method of measurement: Laboratory analysis of the blood samples taken before the intervention and 8 weeks after the commencement of the intervention.;Depression and anxiety. Timepoint: Before the intervention, and 8 weeks after the intervention. Method of measurement: Analysis of the questionnaires filled before the intervention and 8 weeks after the commencement of the intervention.;Antibody HSP27. Timepoint: Before the intervention, and 8 weeks after the intervention. Method of measurement: Laboratory analysis of the blood samples taken before the intervention and 8 weeks after the commencement of the intervention. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Matin Khademi
Mashhad University of Medical Sciences
Outcome results
None listed