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Clinical and histologic comparision of alveolar ridge preservation following tooth extraction using DFDBA & Bio – oss

Clinical and histologic comparision of alveolar ridge preservation following tooth extraction using DFDBA & Bio – oss

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013080414270N1
Enrollment
20
Registered
2014-05-18
Start date
2014-01-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental socket.

Interventions

Intervention 1: Intervention group: will be grafted with 0.5 cc demineralized freeze-dried bone allograft (CenoBone
Tissue Regeneration Corporation, Kish Island, Iranparticle size was 150- 2000 micron ),and Collagen membrane (Bio-gide
Geistlich Pharma) will be trimmed and placed over the grafted socket and alveolar bone. Intervention 2: Control group: will be grafted with (Bio-Oss
Geistlich Pharma, particle size 0.5-1 mm),and Collagen membrane (Bio-gide
Geistlich Pharma) will be trimmed and placed over the grafted socket and alveolar bone.
Treatment - Drugs
Intervention group: will be grafted with 0.5 cc demineralized freeze-dried bone allograft (CenoBone
Control group: will be grafted with (Bio-Oss

Sponsors

President Scientific and Research Assistant
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients must not have any systemic disease and should not take any medication that interferes with bone healing response (like diabetes, autoimmune dysfunction, prolonged corticosteroids therapy or chemotherapy). Also, smokers and those who are allergic to any material uses in this study will be excluded from the study. Only single rooted teeth with buccal plate dehiscence more than 2mm or thickness less than 1mm will be included in the study. In cases with abcess formation, systemic antibiotic including amoxicillin and metronidazole will be given one week prior to extraction.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Bucolingual ridge width. Timepoint: In first surgery and 4-6 months after the first surgery. Method of measurement: Coronal border distance from of buccal aspect to the coronal border of the lingual/palatal aspect of the alveolus or ridge at midpoint(with caliper to the nearest tenth of millimeter; 2).;Alveolar ridge height. Timepoint: In first surgery and 4-6 months after the first surgery. Method of measurement: The distance between the most coronal point of buccal side of the socket or ridge and the most apical end of the stent at the place of its notch, and similar measurement at lingual/palatal aspect(Michigan-O- probe with William marking was used).;Bone formation. Timepoint: 4-6 months after the first surgery. Method of measurement: With image analysis software ( percent).;Type of bone. Timepoint: 4 months after the first surgery. Method of measurement: Optic microscopy.;Residual material. Timepoint: 4 months after the first surgery. Method of measurement: Optic microscopy.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRokhsareh Sadeghi

Dental School of Shahed University

rokh_sadeghi@yahoo.com+98 912 383 1575

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026