Poly Cystic Ovary Syndrome. sclerocystic ovary syndrome-stein leventhal syndrome
Conditions
Interventions
Treatment - Drugs
first group{control group}:treat with Metformin{1500mg/day} orally for 4 months
Intervention 1: first group{control group}:treat with Metformin{1500mg/day} orally for 4 months. Intervention 2: group 2{control group}: treat with Metformin{1500mg/day}plus Calcium{1000mg/day} and Pe
group 2{control group}: treat with Metformin{1500mg/day}plus Calcium{1000mg/day} and Pearl vitamin D3{ 50000IU/ every two weeks} orally for 4 months.
group 3{case group}: treat with Calcium{1000mg/day}and Pearl vitamin D3 {50000IU/every two weeks} orally for 4 months.
group 4{control group}: recieve placebo{low calory sweetener tablets} 2 times a day orally for 4 months
Sponsors
Isfahan University Of Medical Sciences
Eligibility
Sex/Gender
Female
Age
15 Years to 40 Years
Inclusion criteria
Inclusion criteria: include criteria:women in the range of 15-40 years of the age with Poly Cystic Ovary Syndrome that their Calcum(8.7-10.2mg/dl) and Creatinin(0.5-0.9mg/dl) serum are in normal range and they have vitamin D3 serum lower than normal{30ngr/ml}. exclude criteria: Cushing Syndrome?Renal Failur(Creatinin equal or upper than 1.5mg/dl) Ovary and Adrenal Tumor that secreted Androgen?Primary and Secondary hyper Parathyroidism?Osteomalasia?Cancers?Gasterectomy?Mental Retardation?Anti Convuisive Drugs?Congenital Adrenal Hyperplasia and secondary exclude criteria are Diarrhea?Vomiting?severe abdominal Distention.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Regularity of menstural cycle. Timepoint: monthly. Method of measurement: with write of mentural days by patient{interval of regular menses is 24-35days}.;Regularity of menstural cycle. Timepoint: in first and the end of period of treatment. Method of measurement: do sonography for determine of dominant folicle that it is criteria for ovulation and regularity of mense. | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight changes. Timepoint: before start of study and the end of study. Method of measurement: do with determinant of body mass index{BMI}. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSomayeh SHahsavary Alavijeh
Isfahan University Of Medical Sciences
Outcome results
None listed