abnormal uterine and vaginal bleeding. Absent, scanty and rare menstruation, Excessive, frequent and irregular menstruation, Other abnormal uterine and vaginal bleeding
Conditions
Interventions
Intervention 1: In second group intramuscular injection of diphereline 3.75 mg S.R are used before hysteroscopy, starting on day 18 of menstruation every 28 days for 2 month. Intervention 2: In first
Treatment - Drugs
In second group intramuscular injection of diphereline 3.75 mg S.R are used before hysteroscopy, starting on day 18 of menstruation every 28 days for 2 month.
In first group 400 mg Danazol capsules are used every 12 hours placed into the posterior vaginal fornix for 30 days, starting on day 5 of menstruation.
Sponsors
Tabriz University of Medical Sciences, Vice chancellor for Research
Eligibility
Sex/Gender
Female
Age
15 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Women in reproductive age with moderate abnormal uterine bleeding which is resistant to drugs, caused by endometrial hyperplasia; endometrial polyps; submucosal myomas less than 4 cm in size. Exclusion criteria: Patients with Heart, Lung, Renal, Liver disease; Patients with metabolic disease like hypertension, hyperlipidemia, hyperglycemia; Patients with cervical cancers; uterine cancers; submucosal myomas larger than 4 cm in size; Uterine septum; Pregnant women; Patients with genial tract infections; Patients using Anti coagulant drugs; Patients with sever uterine bleeding.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amount of bleeding during operative hysteroscopy. Timepoint: one and two month after administration of Danasol and Diphereline respectively. Method of measurement: visual scale (0-5). | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of hysteroscopy. Timepoint: one and two month after administration of Danasol and Diphereline respectively. Method of measurement: minutes measured by chronometer.;Post operative bleeding. Timepoint: in 24 hour after hysteroscopy. Method of measurement: visual scale (0-5). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Sanam Bidadi
Alzahra University Hospital
Outcome results
None listed