The efficacy of Vitamin D3 on seizure attacks in the patients with drug-resistant epilepsy

Effect of Vitamin D3 on seizure attacks in the patients with drug-resistant epilepsy compared with the control group

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130730014217N2

Enrollment

Registered

2020-02-22

Start date

2018-04-04

Completion date

Unknown

Last updated

2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

drug-resistant epilepsy. Localization-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures, intractable, with status epilepticus

Interventions

Intervention 1: Control group: 22 patients with refractory epilepsy who received placebo at the Faculty of Pharmacy of Isfahan for 8 weeks and once a week. Intervention 2: Intervention group: Twenty-t

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: drug-resistant epilepsy to treatment No other disease Vitamin D3 deficiency Adult population over 18 years.

Exclusion criteria

Exclusion criteria: Patient's unwillingness and conscious dissatisfaction

Design outcomes

Primary

Measure	Time frame
Number of seizures. Timepoint: At beginning and 1, 2 and 3 months after treatment, patients were visited and the number and duration of seizures occurred. Method of measurement: Blood test and evaluation of 25OH vitamin D.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Najafi

Esfahan University of Medical Sciences

najafi@med.mui.ac.ir+98 31 3627 3910

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026