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The effect of Lidocaine on control of emergence agitation due to Sevoflurane

Comparison of two anesthetic regimens Pofol-Lidocaine and Thiopental - Lidocaine on control of emergence agitation due to Sevoflurane in children

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013072914199N1
Enrollment
120
Registered
2013-09-23
Start date
2012-03-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Agitation. Restlessness and agitation

Interventions

Intervention 1: Group2: Pofol 2mg/kg and Lidocaine 1.5mg/kg Pofol administration: IV, Frequency of use: Once and after induction of anesthesia with sevoflurane to maintain anesthesia, Manufacturer: Ge
Treatment - Drugs
Group2: Pofol 2mg/kg and Lidocaine 1.5mg/kg Pofol administration: IV, Frequency of use: Once and after induction of anesthesia with sevoflurane to maintain anesthesia, Manufacturer: Germany Lidocain a
Group1: Was administered Sodium Thiopental 5mg/kg and Lidocaine 1.5mg/kg Lidocain administration: IV, Frequency of use: Once or immediately after an eye examination Manufacturer: Rasht - Iran Sodium T
Group3: Was administered Sodium Thiopental 5mg/kg and an equivalent amount of Saline Sodium Thiopental administration: IV, Frequency of use: Once and after induction of anesthesia with sevoflurane to
Group4: Pofol 2mg/kg and an equivalent amount of Saline Pofol administration: IV, Frequency of use: Once and after induction of anesthesia with sevoflurane to maintain anesthesia, Manufacturer: German

Sponsors

Research Council of Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 3 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Parent willingness to participate in the study and informed consent, Age group: 12 to 36 months, Retinoblastoma eyes Exclusion criteria: A history of seizures, Liver disease, Kidney disease, Heart disease, Having a cold during the current week, Sensitivity to Lidocaine, Intense crying

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Agitation. Timepoint: The scores were recorded every 10 minutes (In the first 30 minutes after entering into recovery), since the children transferred to recovery. Method of measurement: Anesthesiologist divided children into 5 levels based on agitation: 1. Asleep; 2. Awake and calm; 3. Irritable or consolable crying; 4. Inconsolable crying; and 5. Severe restlessness.

Secondary

MeasureTime frame
Nausea and vomiting. Timepoint: The symptoms were recorded every 10 minutes (In the first 30 minutes after entering into recovery), since the children transferred to recovery. Method of measurement: Observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hamidreza Faiz

Rasoul Akram Hospital

hrfaiz@hotmail.com+98 21 6650 9059

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026