Synthesis and Evaluation of the Effect of F.vulgaris Nanofibers on Burn Wounds

Preparation of Nano fiber Containing Pagaze (Falcaria vulgaris) Extract and Studying its Effect on Second-degree Burn Injury Healing Process Compared to Conventional Sterile Gauze Dressing: An Experimental-Clinical Trial Study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130722014106N10

Enrollment

Registered

2023-08-05

Start date

2023-08-23

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Second degree burn injury. Burn of second degree, body region unspecified

Interventions

Intervention 1: First intervention group: after washing and applying conventional treatments, nanofibers containing at least one milligram per square centimeter of Pagaze plant extract will be cut to

Eligibility

Sex/Gender

All

Age

15 Years to 90 Years

Inclusion criteria

Inclusion criteria: Having second-degree burn Referred to "Imam Khomeini" Hospital, Kermanshah, Iran

Exclusion criteria

Exclusion criteria: The survival chance be less than three months Use cytotoxic drugs or radiotherapy Pregnancy or lactation

Design outcomes

Primary

Measure	Time frame
Approximate wound area. Timepoint: Measurement of the approximate wound area before the start of the intervention and 7, 14, 21, 28 and 35 days after the start of dressing with nanofibers containing Pagaze. Method of measurement: Measuring the approximate dimensions of the wound using a ruler and calculating its area.;Scar formation. Timepoint: Before the start of the intervention and 7, 14, 21, 28 and 35 days after the start of dressing with nanofibers containing Pagaze. Method of measurement: Observing the formation or non-formation of scars around the wound.	—

Measure

Time frame

Approximate wound area. Timepoint: Measurement of the approximate wound area before the start of the intervention and 7, 14, 21, 28 and 35 days after the start of dressing with nanofibers containing Pagaze. Method of measurement: Measuring the approximate dimensions of the wound using a ruler and calculating its area.;Scar formation. Timepoint: Before the start of the intervention and 7, 14, 21, 28 and 35 days after the start of dressing with nanofibers containing Pagaze. Method of measurement: Observing the formation or non-formation of scars around the wound.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Tahvilian

Kermanshah University of Medical Sciences

rtahvilian@kums.ac.ir+98 83 1427 6482

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026