Probiotic in treatment of Helicobacterpylory infection

Comparing the effects of Lactobacillus Reuteri and Standard treatment in treatment of infected children with Helicobacter pylori in Imam Ali Hospital in july2012 to November 2013.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013071814048N1

Enrollment

Registered

2013-09-20

Start date

2012-06-13

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacterpylori infection. Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters

Interventions

Intervention 1: drugs in group that received standard treatment includes Amoxicillin50mg/kg/day,Omeprazole1mg/kg/day,Clarythromycin15mg/kg/day for 14 days. Intervention 2: drugs in

Treatment - Drugs

drugs in group that received standard treatment includes Amoxicillin50mg/kg/day,Omeprazole1mg/kg/day,Clarythromycin15mg/kg/day for 14 days.

drugs in group that received standard treatment and Lactobacillus Reuterri includes Amoxicillin50mg/kg/day,Omeprazole1mg/kg/day,Clarythromycin15mg/kg/day, Lactobacillus Reuterri 1tab

Eligibility

Sex/Gender

All

Age

5 Years to 14 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:5-14 years old children; Chronic abdominal pain ; vomiting ;positive Helicobacterpylori infection in Endoscopy . Exclusion criteria:Patients with Antibiotic adminstration;and Proton Pomp Inhibitors or Probiotics in recent two weeks ;Gastric surgery history; Nurologic disease ; Life Threatening disorders.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Vomiting. Timepoint: First and End of treatment. Method of measurement: Physical Exam and questioniear.;Constipation. Timepoint: First and End of treatment. Method of measurement: Physical Exam and questioniear.;Diarrhea. Timepoint: First and End of treatment. Method of measurement: Physical Exam and questioniear.;Nausing. Timepoint: First and End of treatment. Method of measurement: Physical Exam and questioniear.;Abdominal pain. Timepoint: First and End of treatment. Method of measurement: Physical Exam and questioniear.;Heart burn. Timepoint: First and End of treatment. Method of measurement: Physical Exam and questioniear.;Weight loss. Timepoint: First and End of treatment. Method of measurement: Physical Exam and questioniear.	—

Measure

Time frame

Vomiting. Timepoint: First and End of treatment. Method of measurement: Physical Exam and questioniear.;Constipation. Timepoint: First and End of treatment. Method of measurement: Physical Exam and questioniear.;Diarrhea. Timepoint: First and End of treatment. Method of measurement: Physical Exam and questioniear.;Nausing. Timepoint: First and End of treatment. Method of measurement: Physical Exam and questioniear.;Abdominal pain. Timepoint: First and End of treatment. Method of measurement: Physical Exam and questioniear.;Heart burn. Timepoint: First and End of treatment. Method of measurement: Physical Exam and questioniear.;Weight loss. Timepoint: First and End of treatment. Method of measurement: Physical Exam and questioniear.

—

Secondary

Measure	Time frame
Anemia. Timepoint: First and End Of Treatment. Method of measurement: CBC.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Shafighi Shahri

Zahedan University Of Medical Sciences

Eshahri@yahoo.com+98 54 1242 2016

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026