knee osteoarthritis. Gonarthrosis ( arthritis of knee)
Conditions
Interventions
Intervention 1: 1)drug: 500mg garlic tablet twice a day2). Intervention 2: placebo: 500 mg lactose twice a day.
Treatment - Drugs
Placebo
1)drug: 500mg garlic tablet twice a day2)
placebo: 500 mg lactose twice a day
Sponsors
Tehran Uuniversity Of Medical Science
Eligibility
Sex/Gender
Female
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criterias: female, 50-75 years old,25 = BMI = 35, mild or moderate osteoarthritis. Exclusion criteria:severe pain or hip involvement; candidate for surgery; had a knee sergery; sensitivity of garlic; smoking; history of cardiovascular disease; type 1 diabetes; liver disease; hypo or hyper thyroid; kidney disease; arthritis; gout; cancer; any injection in knee in 3 month before intervention; intake of NSAIDs; HRT; astatine; warfarin and supplement like omega 3 or 6 and condroitin sulphate; being in a diet or weight loss about 5% during 3 month in this study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain of knee based on "WOMAC" questionnaire. Timepoint: 3 months. Method of measurement: "WOMAC" questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Body composition. Timepoint: 3 months. Method of measurement: bioelectrical impedance analysis.;Added at 2017-07-15: WOMAC physical function subscale score. Timepoint: Added at 2017-07-15: 12 weeks. Method of measurement: Added at 2017-07-15: questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSahar Dehghani
Tehran University Of Medical Science
Outcome results
None listed