Studying Effect of One Third, Two Third and Normal Saline Serum on Contrast Induced Nephropathy.

Comparative Study of Effect of One Third, Two Third and Normal Saline Serum on Prevention of Contrast Induced Nephropathy in Patients Undergoing Cardiac Angiography.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013071413987N1

Enrollment

100

Registered

2013-11-01

Start date

2013-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Contrast Induced Nephropathy. Paints and dyes, not elsewhere classified

Interventions

Intervention 1: Intervention1:A group of patients will be given sodium bicarbonate plus one third and two third serum randomly, with speed of 1 cc for each kg per hour one hour before, , during and u

7.5 gram sodium bicarbonate, Iran-Samen Pharmaceutical Company. One third and two third serum, each 100 cc contains

3.33 gram dextrose and 0.3 gram sodium chloride, Iran Pharmaceutical Products Company. Intervention 2: Intervention2: Second group of patients will be given sodium bicarbonate plus normal saline serum

Prevention

Intervention1:A group of patients will be given sodium bicarbonate plus one third and two third serum randomly, with speed of 1 cc for each kg per hour one hour before, , during and up to 6 hours aft

7.5 gram sodium bicarbonate, Iran-Samen Pharmaceutical Company. One third and two third serum, each 100 cc contains

3.33 gram dextrose and 0.3 gram sodium chloride, Iran Pharmaceutical Products Company.

Intervention2: Second group of patients will be given sodium bicarbonate plus normal saline serum randomly, with speed of 1 cc for each kg per hour one hour before, , during and up to 6 hours after a

Eligibility

Sex/Gender

All

Age

15 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:Glomerular Filtration Rate(GFR) of below 60 or serum creatinine of above or equal to 1.5 mg/dl. Exclusion criteria:Severe valve diseases and age less than 15 and more than 85 years.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Creatinine. Timepoint: On admission,3 and 5 days after angiography. Method of measurement: Based on milligram per deciliter and by automated analyzer.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Kazem Karimi

Kermanshah University of Medical Sciences

kzk_137253@yahoo.com dr_hashemkazerani@yahoo.com+98 83 1836 2022

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026