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Evaluation of the effect of intravenous acetaminophen in lowering the dose of morphine in renal colic

The comparison of Apotel (intravenous acetaminophen) with intravenous morphine in patients with acute renal colic

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013071411555N1
Enrollment
100
Registered
2014-05-17
Start date
2013-07-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

renal colic. Calculus of kidney and ureter which can cause colicy pain

Interventions

Intervention 1: In intervention group, which the sample will be selected randomly out of 100 patients admitted with acute renal colic, 1 gram of Intravenous Acetaminophen (Apotel) combined with a low
Treatment - Drugs
In intervention group, which the sample will be selected randomly out of 100 patients admitted with acute renal colic, 1 gram of Intravenous Acetaminophen (Apotel) combined with a low dose of Morphine
In Control group, which will be selected randomly from the population of 100 patients admitted with acute renal colic, morphine will be administered intravenously with the dose of 0.1 mg/kg.

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients 18-50 years old; known case of kidney stone. Exclusion criteria: using any drug for pain prior to attendance;, allergy to the administered medications; history of opioid dependence; hypertension; fever and chills ; pregnancy and pain intolerance during the first 35 min of drug administration; pain intolerance during the first 35 min of drug administration.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain severity. Timepoint: 0, 1, 5, 10, 15, 25 and 35 min after drug administered. Method of measurement: visual analogue scale.

Secondary

MeasureTime frame
Probable complications. Timepoint: during procedure until 1 week after discharge. Method of measurement: according to history and physical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hamidreza Mortezabegi

Tabriz University of Medical Sciences

mortezabaghih@tbzmed.ac.ir+98 41 1335 2078

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026