Chronic rhinosinusitis. Chronic pansinusitis
Conditions
Interventions
Intervention 1: Intervention group: Single puff of Desmopressin nasal spray, 30 minutes before starting the surgery in each side of nasal cavity (10 micro gram in each side). This drug complete name i
Sponsors
Hamedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Suffering from chronic rhinosinusitis with or without polyposis Between 18 to 60 years old Normal coagulative tests and platelet count
Exclusion criteria
Exclusion criteria: Suffering from coagulative disorders like Hemophilia Suffering from sinunasal tumors History of thromboembolic accident Suffering from acute or chronic renal failure Receiving Heparin in 48 hour before surgery Receiving Aspirin in 3 days before surgery Allergy to Desmopressin Liver scirrhosis Systemic diseases like hypertension, diabet mellitus, heart failure Pregnancy Cardiac stent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual field of surgery. Timepoint: 15,30,60,90 minutes after starting surgery. Method of measurement: Boezaart Grading.;Bleeding volume. Timepoint: 15,30,60,90 minutes after starting surgery. Method of measurement: blood volume in suction s bottle. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure. Timepoint: before and in points of 15,30,60 and 90 min after surgery. Method of measurement: blood pressure monitoring.;Surgery duration. Timepoint: time of starting upto end of the surgery. Method of measurement: recording duration of surgery.;Serum sodiume level. Timepoint: before and after the surgery. Method of measurement: serum sodiume level test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactElham Tayebi
Hamedan University of Medical Sciences
Outcome results
None listed