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Comparison of the drugs seizure control

Comparison of the seizure control with intravenous sodium valproate and Phenobarbital in children who referred to Ali-Ebn-Abitaleb hospital in Zahedan in 2012-2013.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013071113956N1
Enrollment
80
Registered
2013-09-11
Start date
2012-08-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Seizure. Episodic and paroxysmal disorders

Interventions

Intervention 1: With the drug phenobarbital dose of 20 mg per kg body weight,single dose,in control group, within 20 minutes of seizure control is considered a positive response. Intervention 2: Wit
Treatment - Drugs
With the drug phenobarbital dose of 20 mg per kg body weight,single dose,in control group, within 20 minutes of seizure control is considered a positive response
With the drug sodium valproatel dose of 20 mg per kg body weight,single dose,in interventionl group, within 20 minutes of seizure control is considered a positive response

Sponsors

Research Assistant zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 14 Years

Inclusion criteria

Inclusion criteria: we enrolled children who were experiencing convulsions while attending emergency rooms and whose seizures were not controlled by a bolus of intravenous diazepam (0.2 mg/kg) within 5 min. We excluded children with a history of adverse reactions to sodium sodium valproate or similar drugs, a history of uncontrolled bleeding, thrombocytopaenia, active hepatic disease, cardiac rhythm disturbances orthostatic hypotension, or syncope.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Response to treatment. Timepoint: once after intervention then 20 minutes later. Method of measurement: View seizure control or lack of control.;Recovery time. Timepoint: once after intervention then 20 minutes later. Method of measurement: measurement duration of seizure control with time unit(minite).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeedeh Yaghoobi

Zahedan University of Medical Sciences

zahedan.medical@gmail.com+98 54 1341 4570

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026