The effect of Tranexamic acid in bleeding and echymosis in corrective nose surgery

Comparison the efficacy of Tranexamic acid in intervention and placebo groups in rhinoplasty patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013071013938N1

Enrollment

Registered

2014-07-12

Start date

2013-08-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bleeding ,Oedema and Echymosis. Anaesthetics and therapeutic gases

Interventions

Intervention 1: IV adminstration of 10 mg/kg tranexamic acid just befor begining of surgery. Intervention 2: 20 ml normal saline IV injection as placebo.

Treatment - Drugs

IV adminstration of 10 mg/kg tranexamic acid just befor begining of surgery

20 ml normal saline IV injection as placebo

Eligibility

Sex/Gender

All

Age

19 Years to 39 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Healthy Men and Female; Age range between 19- 39. Exclusion criteria: Men and Female between 19- 39 years old with Systemic and Methabolic diseases.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Bleeding. Timepoint: Just after intervention. Method of measurement: x=volum of suction+ (weight of bloody guazes - weight of dry guazes) total bleeding=x-volum of irigation fluides uses in surgery.	—

Secondary

Measure	Time frame
Oedema. Timepoint: 24 hours after surgery. Method of measurement: Standarad 4 scale system.;Echymosis. Timepoint: 24 hours after surgery. Method of measurement: Standarad 4 scale system.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Ali Ghavimi

Tabriz University of Medical Sciences

ghavimim@tbzmed.ac.ir+98 41 1335 5965

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026