Comparison of Intra-cytoplasmic sperm injection outcomes during two sperm selection procedures: Density Gradient Centrifuging and response to Hypo Osmotic Swelling medium in male factor infertile patients

Comparison of ICSI outcome in two sperm selection method: routine sperm selection and HOS method in infertile men

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201307087223N2

Enrollment

Registered

2013-10-27

Start date

2012-08-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male infertilty. Male infertility

Interventions

Intervention 1: in control group: Endometer quality in the day of embryo transfer: if uterine endometer has a bad quality, good embryo freeze and low quality embryo may transferred that affect pregnan

in control group: Endometer quality in the day of embryo transfer: if uterine endometer has a bad quality, good embryo freeze and low quality embryo may transferred that affect pregnancy outcome

in test group: Endometer quality in the day of embryo transfer: if uterine endometer has a bad quality, good embryo freeze and low quality embryo may transferred that affect pregnancy outcome

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: male factor infertility;oocyte number up to 8 Exclusion criteria: age>35, female factor infetility

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pregnancy rate. Timepoint: 2 weeks after embryo transfer. Method of measurement: beta hCG test.	—

Secondary

Measure	Time frame
Fertilization rate. Timepoint: 24 for after injectin sperm into oocyte during ICSI. Method of measurement: observation of two pronucleus under microscope.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Hossein Nasr Esfahani

Royan institute

mh_nasr@med.mui.ac.ir+98 21 2356 2123

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026