burn. Burn of second degree, body region unspecified, Burn of third degree, body region unspecified
Conditions
Interventions
Intervention 1: Hospital routine Nutrition
(Control Group). Intervention 2: (Intervention Group1) energy requirement is calculated by harris benedict equation, enteral nutrition starts with 25ml/h ent
Treatment - Other
Hospital routine Nutrition
(Control Group)
(Intervention Group1) energy requirement is calculated by harris benedict equation, enteral nutrition starts with 25ml/h enteral standard formula and increases to goal. Duration of intervention is ten
Intervention Group 2: energy requirement is calculated by harris benedict equation, enteral nutrition starts with 25ml/h standard enteral formula and increases to goal. 50 mg/kg BW.day of Taurine is g
Sponsors
Research Center of Infectious and Tropical Diseases, Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Burned patients between the age18 and 85 years with total body surface area of burn more 20%; enteral feeding requirement of at least 48 h and expected length of >48h stay in the ICU; patients without hepatic failure; renal failure; inborn errors of amino-acid metabolism; metabolic acidosis(pH less7.35); absolute contraindication to enteral nutrition; non pregnant woman. Exclusion criteria: patients who died before the end of intervention; patients unable to tolerate enteral feeding.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical outcome measurement. Timepoint: day 1,3,6,9. Method of measurement: Sequential Organ Failure Assessment(SOFA) score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Effect on Immune System. Timepoint: Baseline and end of intervention. Method of measurement: TNF-alpha(ELISA test), Interleukin 10(IL-10)(ELISA test), High sensitivity C reactive protein( hs-CRP)(ELISA test).;Effect on Nutritional Status. Timepoint: Baseline and end of intervention. Method of measurement: Prealbumin (Immunoturbidometric assay). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSima lak
Faculty of Nutrition, Tabriz University of Medical Sciences
Outcome results
None listed