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Effect of injection order of the Diphtheria-Pertussis-Tetanus vaccine and Hepatitis B vaccine on pain in infants

The comparison of injection order of the Diphtheria-Pertussis-Tetanus vaccine and Hepatitis B vaccine on pain response in infants

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013070713889N1
Enrollment
140
Registered
2013-12-22
Start date
2012-12-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The Pain of vaccine. pain in limb

Interventions

Intervention 1: Intervention group: First the 0.5ml Hepatitis B vaccine manufactured by Pasteur Institute of Iran injected intramuscularly and then the 0.5ml DTP vaccine manufactured by Pasteur Compan
Prevention
Intervention group: First the 0.5ml Hepatitis B vaccine manufactured by Pasteur Institute of Iran injected intramuscularly and then the 0.5ml DTP vaccine manufactured by Pasteur Company of Indonesia i
Control group: Routine order administered.(First the 0.5ml DTP vaccine manufactured by Pasteur Company of Indonesia injected intramuscularly and then the 0.5ml Hepatitis B vaccine manufactured by Past

Sponsors

Vice chancellor for research,Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 3 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: 1. Healthy two month-old infants of both sexes with complete consciousness. 2. No history of surgery or hospitalization 3. Absence of chills, fever, diarrhea, etc. Exclusion criteria: taking analgesic or sedative drug 24 hours before vaccination by the infant or her mother.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Behavioral pain responses. Timepoint: Immediately after vaccine injection until 15 seconds. Method of measurement: Modified Behavioral Pain Scale (MBPS).

Secondary

MeasureTime frame
Duration of crying. Timepoint: Immediately after vaccine injection up to time infants calm down or,maximum up to 3 minutes after injection. Method of measurement: Using stop watch(second).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatihe Kerman Saravi

Zahedan University of Medical Sciences

Fatihe @yahoo.com+98 54 1241 1515

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026