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Comparison of the efficacy of antibiotics on infectious complications after laparoscopic surgery for patients with Cholecystitis

Comparison of the efficacy of antibiotics on infectious complications after laparoscopic surgery for patients with Cholecystitis

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013070413865N1
Enrollment
100
Registered
2014-04-28
Start date
2013-05-26
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic cholecystitis. Chronic cholecystitis

Interventions

Intervention 1: Intervention group cefazolin 25 mg / Kg intravenous before transfer to the operating room by the nurse and two doses every 6 hours after surgery, the patient is injected. Intervention
Treatment - Surgery
Intervention group cefazolin 25 mg / Kg intravenous before transfer to the operating room by the nurse and two doses every 6 hours after surgery, the patient is injected.
Regimen is not recommended for patients in the control group

Sponsors

Deputy of Reaserch and Technology of Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 74 Years

Inclusion criteria

Inclusion criteria: (Inclusion criteria: age less than 75 years; absence of immuned eficiency diseases; lack of endoscopic retrograde cholangiopancreatography in recent weeks; antibiotics a week before laparoscopy; no common bile duct stones; no diagnosis of acute cholecystitis with gallstones (based on clinical findings and clinical); diagnosis of pancreatitis and cholangitis; Exclusion criteria were: age over 75 years; the immune system is compromised; previous endoscopic retrograde cholangiopancreatography in recent weeks (due to antibiotics); antibiotics a week before laparoscopy; Common bile duct stones; acute cholecystitis with gallstones (based on clinical findings and clinical); pancreatitis and cholangitis; in cases where severe bleeding occurs during surgery or in the tear ducts bile and gallbladder due to needing antibiotics after surgery; all cases requiring surgical drains are in place)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Surgical Site Infection. Timepoint: Five days after surgery. Method of measurement: Clinical.

Secondary

MeasureTime frame
Respiratory Infection. Timepoint: 24-72 hours after surgery. Method of measurement: Clinical.;Fever and Chills. Timepoint: 24-72 hours after surgery. Method of measurement: Clinical.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlieh Nikmanesh

Babol University of Medical Sciences

Hidekey-2@yahoo.com+98 11 1225 6285

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 13, 2026