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Compare the effect of combined methylergonovine pill and combined oral contraceptive low dose (LD) with methylergonovine and LD pills alone on bleeding caused by retention product of pregnancy after first trimester of abortion

Compare the effect of combined methylergonovine pill and combined oral contraceptive low dose (LD) with methylergonovine and LD pills alone on bleeding caused by retention product of pregnancy after first trimester of abortion

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013070213845N1
Enrollment
111
Registered
2014-01-20
Start date
2013-07-13
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Retained products of conception. Early fetal death with retention of dead fetus

Interventions

Intervention 1: Methyleregonovine tablet 0/25 mg (TID for one week) with LD tablet (once in day for 21 days). Intervention 2: Methylergonovine tablet (0/25 mg TID for one week). Intervention 3: LD tab
Treatment - Drugs
Methyleregonovine tablet 0/25 mg (TID for one week) with LD tablet (once in day for 21 days)
Methylergonovine tablet (0/25 mg TID for one week)
LD tablet (once /day for 21 days)

Sponsors

Vice chancellor for Research, Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: woman with age between 20-35 first trimester abortion with bleeding or sonography that show retain tissue, HB 11 gr/dl or more, no history of angina, Myocardial infarction, Cardiovascular disease, Coronary artery disease, no history of Cerebrovascular Diseases, Transient ischemic attacks and Severe migraine, no history of Eclampsia and pre eclampsia, Severe hypertension, Peripheral arterial occlusive disease, no history of Thrombophlebitis and thromboembolic disorders, no history of Liver adenoma, Carcinoma or Benign tumors of the liver, Liver dysfunction and acute liver disease, No-smoking exclusion criteria: Unwillingness to cooperate, Allergic reactions to medicines, Hemoglobin decreased during the study (10 gr/dl or less)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Complete pass of residual products of conception. Timepoint: After the intervention period. Method of measurement: Sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKhadijeh abdali

Fatemeh College of Nursing And Midwifery,Shiraz University of Medical Sciences

abdali_kh@yahoo.com+98 71 1647 4254

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026