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Comparing the effect of Pulsed and Conventional Radiofrequency celiac plexus neurolysis on Abdominal Cancer Pain

Comparing the effect of Pulsed and Conventional Radiofrequency celiac plexus neurolysis on Abdominal Cancer Pain

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201306307984N9
Enrollment
50
Registered
2013-09-11
Start date
2012-05-08
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal cancers. Malignant neoplasm of pancreas

Interventions

Intervention 1: The patients are first divided into 2 groups each containing 25 persons. In the first group or the PRF group, celiac plexus block would be performed under fluoroscopy and sterile condi
Treatment - Other
Treatment - Drugs
The patients are first divided into 2 groups each containing 25 persons. In the first group or the PRF group, celiac plexus block would be performed under fluoroscopy and sterile condition after placi
In the second group the same method is used except for the final stage for which the conventional mode with RF cycles of 90 degrees and for 90 seconds will be used twice with an interval of 30 seconds

Sponsors

Tehran university of medical sciences, Vice-chancellor for research
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Iinclusion criteria: Age range of 20 to 60 years old ; painful non-operable abdominal cancer Exclusion criteria: Renal failure; Pregnancy; Allergy to Ropivacaine and Opioid; Significant coexisting disease (CNS or cardiovascular problems)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Visual analogue score according to the designed pain ruler. Timepoint: Weekly for 3 consecutive months. Method of measurement: Visual analogue score is measured with a marked ladder from 0 to 10.;The amount of analgesic used. Timepoint: Weekly for 3 consecutive months. Method of measurement: The percentage of the used analgesic is measured by dividing the amount of analgesic after the block by the amount before the block and then multiplying the result by 100.

Secondary

MeasureTime frame
Blood pressure changes. Timepoint: Before the intervention and 3 weeks thereafter. Method of measurement: Measured with digital sphygmomanometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Farnad Imani

Tehran university of medical sciences

farimani@tums.ac.ir+98 21 6435 2107

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026