General anesthesia. Other and unspecified general anaesthetics
Conditions
Interventions
Intervention 1: In A group, propofol is infused with infusion rate equals to 50µg/kg/min. Intervention 2: In B group, propofol is infused with infusion rate equals to 100µg/kg/min.
Treatment - Drugs
In A group, propofol is infused with infusion rate equals to 50µg/kg/min.
In B group, propofol is infused with infusion rate equals to 100µg/kg/min.
Sponsors
Ahvaz Jundishapour University of Medical Sciences
Eligibility
Sex/Gender
All
Age
17 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: ASAclass-1; Age between15-55 years. Exclusion criteria: ASAclass-2; Addiction; Liver, kidney, cardiac disease; Sensivity for egg; Hemodynamic instability.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma concentration of propofol. Timepoint: If possible blood samples are collected at 0, 2, 5, 10, 15, 30, 45, 60 minutes during infusion and then 0, 2, 5, 10, 15, 30, 45, 60, 120, 180 minutes after the end of infusion. Method of measurement: Blood sampling with the volume of 2ml and analyzing the concentration with HPLC.;Weight. Timepoint: Before transfering to operation room. Method of measurement: Scale.;Height. Timepoint: Before transfering to operation room. Method of measurement: Meter.;Age. Timepoint: Before transfering to operation room. Method of measurement: Match with birth certificate.;Sex. Timepoint: Before transfering to operation room. Method of measurement: Match with birth certificate. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Saeed Rezaee
School of pharmacy, Ahvaz Jundishapur University of Medical Sciences
Outcome results
None listed