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Comparison of the effect of intrauterine misoprostol administration with sublingual in second trimester abortions induction

Comparison of the effect of intrauterine misoprostol administration with sublingual in second trimester abortions induction

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130626013777N3
Enrollment
86
Registered
2022-07-08
Start date
2022-07-01
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Therapeutic Abortion. Therapeutic/Medical Abortion (termination of pregnancy)

Interventions

Intervention 1: The first group includes intrauterine administration of misoprostol. A catheter under direct vision and under sterile conditions using chlorhexidine or betadine by using the vaginal sp

Sponsors

Vice chancellor for Research,Tabriz University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
16 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 16 years Gestational age 14 to 22 weeks based on first trimester ultrasound Consent to participate in the study Having an indication for termination of pregnancy

Exclusion criteria

Exclusion criteria: Coagulation disorders or taking anticoagulant Possibility of ectopic pregnancy Probability of molar pregnancy Women with an IUD Women with a history of one or more cesarean sections or a history of uterine incision or myoctomy Pregnancy of placenta peria ?? Parity 5 times or more

Design outcomes

Primary

MeasureTime frame
The time interval between induction of abortion and excretion of pregnancy products. Timepoint: From the beginning of the intervention until the complete rejection of the fetus. Method of measurement: Clinical examination and ultrasound.

Secondary

MeasureTime frame
Fever. Timepoint: Every 4 hours from the beginning of the intervention until the complete abortion of the fetus. Method of measurement: Thermometer.;Nausea. Timepoint: Every 4 hours from the beginning of the intervention until the complete abortion of the fetus. Method of measurement: Clinical examination.;Vomiting. Timepoint: Every 4 hours from the beginning of the intervention until the complete abortion of the fetus. Method of measurement: Clinical examination.;Chills. Timepoint: Every 4 hours from the beginning of the intervention until the complete abortion of the fetus. Method of measurement: Clinical examination.;Chills. Timepoint: Every 4 hours from the beginning of the intervention until the complete abortion of the fetus. Method of measurement: Clinical examination.;Headache. Timepoint: Every 4 hours from the beginning of the intervention until the complete abortion of the fetus. Method of measurement: Clinical examination.;Skin rash. Timepoint: Every 4 hours from the beginning of the intervention until the complete abortion of the fetus. Method of measurement: Clinical examination.;Dizziness. Timepoint: Every 4 hours from the beginning of the intervention until the complete abortion of the fetus. Method of measurement: Clinical examination.;Dfficulty breathing. Timepoint: Every 4 hours from the beginning of the intervention until the complete abortion of the fetus. Method of measurement: Clinical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShamsi Abbasalizadeh

Tabriz University of Medical Sciences

shamciabbasalizadeh@gmail.com+98 41 1553 9161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026