Termination of pregnancy in the second trimester. Medical abortion
Conditions
Interventions
Intervention 1: Intervention group: 7.5 mg ? letrozole (Manufacturing Iran Hormones Company) prescribed up to three doses at home, the patient was hospitalized on the fourth and Misoprostol 400 microg
Sponsors
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Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: patients more than 18 years of age Gestational age of 13 to 26 with an indication for termination of pregnancy in medical method Hb above 10 Reason for termination of pregnancy, such as missed abortion; Pregnancy NULL; Therapeutic abortion legal authorization and consent of patients BMI between 25-25
Exclusion criteria
Exclusion criteria: Pain and bleeding Drug sensitivity to misoprostol; Severe anemia Coagulopathy or taking anticoagulants Active liver disease Cardiovascular disease and uncontrolled seizures Adrenal disease history of corticosteroid use
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abortion. Timepoint: The start of the intervention up to 24. Method of measurement: Ultrasound.;Time between medication abortion. Timepoint: The start of the intervention up to 24. Method of measurement: hour.;The need for curettage. Timepoint: Seven days after abortion. Method of measurement: Clinical. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: Intervention to 24 hours after administration. Method of measurement: Clinical. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShamsi Abbasalizadeh
Tabriz University of Medical Sciences
Outcome results
None listed