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The effect of anesthetic medications on the quality of electrocunvulsive therapy

The effects of Ketamin versus Thiopental sodium on hemodynamic profile and seizure duration in ECT patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201306255026N3
Enrollment
40
Registered
2013-07-11
Start date
2013-06-26
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Major depression without psychotic feature. Condition 2: Major depression with psychotic feature. Severe depressive episode without psychotic symptoms Severe depressive episode with psychotic symptoms

Interventions

Intervention 1: ketamin 0.3 mg/kg for induction of anesthesia. Intervention 2: Sodium Thiopental 0.2 mg/kg for induction of anesthesia.
Treatment - Drugs
ketamin 0.3 mg/kg for induction of anesthesia
Sodium Thiopental 0.2 mg/kg for induction of anesthesia

Sponsors

Vice chancellor for Research, Tehran university of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Major depression candidate for electroconvulsive therapy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Heart rate. Timepoint: before induction, 1, 3 and 10 minutes after induction. Method of measurement: ECG monitoring.;Blood pressure. Timepoint: before induction, 1, 3 and 10 minutes after induction. Method of measurement: mm Hg using noninvasive blood pressure monitoring.;Duration of seizure. Timepoint: after termination of seizure. Method of measurement: Chronometer.—

Secondary

MeasureTime frame
Nausea. Timepoint: discharge from recovery. Method of measurement: direct question from patients and recording in data collection form.—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasood Mohseni

Tehran University of Medical Sciences

m-mohseni@tums.ac.ir+98 21 6435 2326

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026