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The effect of transexamic acid and medroxyprogestrone on puerperal bleeding

The comparisone of effects of Transexamic acid and Medroxyprogestrone on puerperal bleeding

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201306193461N6
Enrollment
66
Registered
2013-08-06
Start date
2013-04-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

puerperal bleeding. complications of the the puerperium unspecified

Interventions

Intervention 1: Group A:every 12 hour,250 mg oral transexamic acid capsule with two ferrous sulfate is given. Intervention 2: Group B: every 12 hour 1 tablet 5 mg medroxyprogestrone with two ferrous
Treatment - Drugs
Group A:every 12 hour,250 mg oral transexamic acid capsule with two ferrous sulfate is given.
Group B: every 12 hour 1 tablet 5 mg medroxyprogestrone with two ferrous sulfat is given

Sponsors

Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criterias: women 15-45 ages with prolonged puerperal bleeding; dizziness; hypotension; skin allergy because of tampone use;and 30 days after delivery. Exclusion critreias: Birth canal lacerations; retained placenta; myoma and endometrial polyps; history of chronic diseases such as: hepatic, renal,diabetes, thromboembolic and coagulative disorders; anticoagulative drug use ; and thrombocytopenia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

MeasureTime frame
Headache and dizziness. Timepoint: Before and six weeks after intervention. Method of measurement: Patient report.;Spotting. Timepoint: Before and six weeks after intervention. Method of measurement: Patient report.;Repeat intervention. Timepoint: Up to six weeks after intervention. Method of measurement: Surgery,D&C,administration of drug.

Primary

MeasureTime frame
The volume of bleeding. Timepoint: Before and six weeks after intervention. Method of measurement: The number of used pads before and after intervention.;Hb level. Timepoint: Before and six weeks after intervention. Method of measurement: Hb level measurement.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactfiroozeh veisi

Kermanshah University of Medical Sciences

f_veisi@kums.ac.ir firoozehveisi@yahoo.com+98 83 1427 6309

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026