Comparison of effect of bupropion and venlafaxine in children with hyperactivity

Comparison of therapeutic effect of bupropion and venlafaxine in children with Attention deficit hyperactivity disorder

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201306189175N5

Enrollment

Registered

2013-07-12

Start date

2011-12-19

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention deficit hyperactivity disorder. Attention deficit: disorder with hyperactivity, hyperactivity disorder and syndrome with hyperactivity

Interventions

Intervention 1: First group: The patients will be received ritalin with previous dose beside venlafaxine 0.5 mg to Kg weight during the first week. In the second week, half of the first week ritalin d

Treatment - Drugs

First group: The patients will be received ritalin with previous dose beside venlafaxine 0.5 mg to Kg weight during the first week. In the second week, half of the first week ritalin dose beside venla

For the second group: In the first week of 1.4 mg per kg body weight bupropion (beside previous dose ritalin) is given. In the second week, half of the Ritalin dosage beside 1.91 mg per kg body weight

Eligibility

Sex/Gender

All

Age

7 Years to 10 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Children with attention deficit hyperactivity disorder between 7 to 10 years old with IQ more than 70 by Rion quiz and have not any psychiatric and neurological problem at interview. Exclusion criteria: Children with attention deficit hyperactivity disorder lower than 7 years old and more than 10 years old, IQ lower than 70 and any psychiatric and neurological problem at interview.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Percentage of response to treatment. Timepoint: before the study, after each two weeks and after completing the study. Method of measurement: Connors Parent Questionnaire.;Percentage of response to treatment. Timepoint: before the study, after each two weeks and after completing the study. Method of measurement: Clinical Global Impression Scale.;Percentage of response to treatment. Timepoint: before the study, after each two weeks and after completing the study. Method of measurement: Attention deficit hyperactivity disorder rating scale IV.	—

Measure

Time frame

Percentage of response to treatment. Timepoint: before the study, after each two weeks and after completing the study. Method of measurement: Connors Parent Questionnaire.;Percentage of response to treatment. Timepoint: before the study, after each two weeks and after completing the study. Method of measurement: Clinical Global Impression Scale.;Percentage of response to treatment. Timepoint: before the study, after each two weeks and after completing the study. Method of measurement: Attention deficit hyperactivity disorder rating scale IV.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Peiman Hashemian

Mashhad University of Medical Sciences

hashemianp@mums.ac.ir+98 51 1888 2926

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026