Ideal time for contact lens removal after photorefractive keratectomy

Comparison of the effect of contact lens removal time in inducing pain after photorefractive keratectomy in refractive surgery candidates

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013061613567N3

Enrollment

Registered

2013-11-13

Start date

2013-11-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperopia-myopia. mild or no visual impairment, binocular

Interventions

Intervention 1: For the experimental group, bandage contact lens is removed 7th day after surgery and three different eye drops are administered for the following weeks : chloramphenicol 0.1% every si

Treatment - Other

For the experimental group, bandage contact lens is removed 7th day after surgery and three different eye drops are administered for the following weeks : chloramphenicol 0.1% every six hours for four

For the control group, bandage contact lens is used right after surgery and removed after 4 days. Three different eye drops are administered for the following week: chloramphenicol 0.1% every six hou

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Over 18 year of age, Less than 0.5 Diopter change in visual acuity in the previous year, Myopia -1.0 to -6.0, Astigmatism 0.75 to 3.0, Hyperopia +1.0to +4.0, Corneal stroma more than 450 micron, Pupil size less than 6mm. Exclusion criteria: Keratoconus, Herpetic keratitis, Corneal dystrophy, Corneal degeneration, Cataract, Glaucoma, Dry eye, Lag ophthalmos, Uveitis, Blepharitis, diabetes, Pregnancy, Breast feeding, Auto immune disease, Immunodeficiency, History of keloid formation.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Ocular discomfort (including pain, epiphora, foreign body sensation, blurred vision and photophobia). Timepoint: Fourth and seventh day post operation. Method of measurement: Questionnaire.;Visual acuity. Timepoint: On the first, third and sixth month after surgery. Method of measurement: snellen chart.;Aberration. Timepoint: Sixth months after surgery. Method of measurement: aberrometry.;Corneal haze. Timepoint: On the first, third and sixth month after surgery. Method of measurement: Slit lamp.	—

Measure

Time frame

Ocular discomfort (including pain, epiphora, foreign body sensation, blurred vision and photophobia). Timepoint: Fourth and seventh day post operation. Method of measurement: Questionnaire.;Visual acuity. Timepoint: On the first, third and sixth month after surgery. Method of measurement: snellen chart.;Aberration. Timepoint: Sixth months after surgery. Method of measurement: aberrometry.;Corneal haze. Timepoint: On the first, third and sixth month after surgery. Method of measurement: Slit lamp.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehrdad Mohammad pour

Tehran University of medical science

mahammadpour@yahoo.com+98 21 5542 1006

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026