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The effect of L-arginine with vitamin C supplementation on nitrogen balance , body composition, VO2max, serum growth hormone, testosterone and cortisol in male body builders

The effect of L-arginine with vitamin C supplementation on nitrogen balance , body composition, VO2max, serum growth hormone, testosterone and cortisol in male body builders

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130616013678N28
Enrollment
54
Registered
2019-02-14
Start date
2018-07-01
Completion date
Unknown
Last updated
2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: l-arginine and vitamin c supplementation. Condition 2: athletic performance,vo2max. Condition 3: nitrogen balance. Condition 4: Growth Hormone ,testosterone and cortisol. Condition 5: male body builders.

Interventions

Intervention 1: Intervention group: The first group will receive a 3 gram L-Arginine supplement(karen pharmaceutical company) per day with 500 mg vitamin C (Jalinous pharmaceutical company) for the

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: tend to participate in the study male gender; Due to better access to male athletes rather than female athletes and tend to use supplemen healthy people age group between 18-35 years old Participants have done strength training for at least 1 year 3 times a week

Exclusion criteria

Exclusion criteria: Consumption of anabolic drugs Using cigarette and alcohol Consumption of vitamin C and L-arginine supplement before the intervention Having a certain diet Consumption of any supplement during the study People with cardiovascular diseases, pulmonary disease, diabetes, hypertension, acute psychiatric disorders, cold, inflammatory diseases, hypothyroidism Physical injury and illness during the intervention period Consumption of anti-inflammatory agents before and during the intervention Consumption of other supplements at least one month before the intervention

Design outcomes

Primary

MeasureTime frame
Growth Hormone. Timepoint: before and 6 weeks after trials. Method of measurement: lab test.;Testostrone Hormone. Timepoint: before and 6 weeks after trials. Method of measurement: lab test.;Cortisol Hormone. Timepoint: before and 6 weeks after trials. Method of measurement: lab test.;Nitrogen Balance. Timepoint: before and 6 weeks after trials. Method of measurement: lab test(24 hours urine collection and measurement of nitrogen urinary urea ) and 24 hours recall (Determination of protein intake and calculation of nitrogen intake).;Body composition (fat and protein percentage). Timepoint: before and 6 weeks after trials. Method of measurement: Body composition analyzer (BIA).;Maximal oxygen consumption. Timepoint: before and 6 weeks after trials. Method of measurement: Queens step Test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Saeed Ghavamzadeh

Oroumia University of Medical Sciences

Ghavamzadeh_s@yahoo.com+98 44 3278 0803

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026