The evaluation of probiotic drug of Lactol in symptomatic treatment of Small- Intestinal Bacterial Over Growth (SIBOG) syndrome

Evaluating the efficacy of Lactol probiotic on treatment of Small-Intestinal Bacterial Over Growth Syndrome(SIBOG)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013061313662N1

Enrollment

Registered

2013-07-14

Start date

2010-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Small-Intestinal Bacterial Over Growth (SIBOG) syndrome. Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Interventions

Intervention 1: Study group: Monthly maintenance therapeutic regimen including 15 days of antibiotic therapy with Minocycline (100 mg Bid) and 15 days with Lactol probiotic (Bid after meals) for 6 mo

Treatment - Drugs

Study group: Monthly maintenance therapeutic regimen including 15 days of antibiotic therapy with Minocycline (100 mg Bid) and 15 days with Lactol probiotic (Bid after meals) for 6 month period.

Control group: Monthly maintenance therapeutic regimen including 15 days of antibiotic therapy with Minocycline (100 mg Bid) during first half of each month for 6 month period.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients with chronic stomach pain and discomfort or changes in their defecation with no other anatomical or functional diagnosis rather than Small-Intestinal Bacterial Over Growth (SIBOG); Positive Hydrogen Breath Test (HBT) regarding SIBOG Exclusion criteria: Existence of other GI pathology rather than SIBOG; usage of Antibiotic, Bismuth, PPI

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Level of respiratory hydrogen. Timepoint: At the beginning of study & After 6 month. Method of measurement: Hydrogen Breath Test (HBT).	—

Secondary

Measure	Time frame
GI symptoms. Timepoint: At the beginning of study & after 6 month. Method of measurement: Digestive symptoms questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Reza Behdani

Medical faculty, Islamic Azad University of Mashhad

behdani.reza@gmail.com+98 51 1761 9929

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026