Effects of different anesthetic agents in patients with controlled hypertension

Comparison of effect of three local anesthesia including lidocaine 2% epinephrine 1/80000, prilocaine 3% flypressin 0/03%, plain mepivacaine 3% on blood pressure in hypertensive patients before tooth extraction

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013061013621N1

Enrollment

Registered

2013-06-23

Start date

2013-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood pressure of patients. Examination of blood pressure

Interventions

Intervention 1: Two anesthetic cartridges containing lidocaine 2% epinephrine 1/80000. Intervention 2: Two anesthetic cartridges containing prilocaine 3% flypressin 0/03%. Intervention 3: Two anesth

Treatment - Drugs

Two anesthetic cartridges containing lidocaine 2% epinephrine 1/80000

Two anesthetic cartridges containing prilocaine 3% flypressin 0/03%

Two anesthetic cartridges containing mepivacaine 3%

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients who need inferior alveolar nerve block injection to extraction teeth; patients with high blood pressure but under control and below 94/159 mmHg. Exclusion criteria: cardiovascular disease: unstable angina, myocardial infarction before 6 months, 6 months following cerebrovascular accident, CABG under 6 months, uncontrolled cardiac arrhythmias, decompensated congestive heart disease; untreated hyperthyroid, uncontrolled diabetes mellitus; sulfate-sensitive asthma, real allergies to sulfites; pregnant and lactating women.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: 3 times: 5 min before injection, immediately after injection and 5 min after injection. Method of measurement: Blood pressure is measured in millimeters of mercury with a pulse oximeter.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShamsoodin Rigi

Zahedan University of Medical Science

shams554@ymail.com+98 54 1244 1814

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026